This drug may interfere with the absorption of orally administered griseofulvin, lowering its blood levels; effects of blood amount reduction unfamiliar; preferable to stay away from concomitant administration of those drugs pentobarbital will decrease the extent or effect of ramelteon by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unknown. pentobar... https://lukasohtfs.thekatyblog.com/30149674/what-type-of-drug-is-nembutal-no-further-a-mystery