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Butabarbital decreases effects of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Coadministration of CYP3A4 inducers may well reduce sufentanil concentrations and efficacy, quite possibly precipitating withdrawal syndrome in individuals who've formulated Bodily dependence to sufentanil. Discontinuation of concomitantly applied CY... https://johnnyk918uel4.wikitidings.com/user

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